A severe jawbone problem called osteonecrosis has rarely been reported with Prolia. Mild side effects can occur with Prolia use. We study millions of patients and 5,000 more each day. They will also explain how much youll be given and how often. Youll get Prolia injections from a healthcare professional once every 6 months. Your doctor may suggest limiting foods that are high in trans fats, such as fried foods. We avoid using tertiary references. Mild side effects that have been reported with Prolia include: These side effects may be temporary, lasting a few days or weeks. This medication guide provides information about the Prolia brand of denosumab. Prolia comes as a solution thats given as an injection under your skin. They may want to check for other causes. Learn about compression fractures, preventive medications, and, Preventing osteoporosis can help you prevent fractures and maintain strength as you age. For a basic overview of Prolia, including details about its uses, see this article. Your healthcare professional might talk to you about taking a calcium or vitamin D supplement, although generally its better to get enough of each from your diet. Continue reading. Calcium and Vitamin D: A major role of vitamin D is to help the body absorb calcium and maintain bone density. They can also tell you about other treatment options available for osteoporosis and bone loss prevention. It may not cover all possible information. Prolia is available as the biosimilar medication denosumab. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Your doctor or pharmacist can tell you more about the potential side effects of Prolia and ways to reduce them. For a detailed breakdown of Prolia versus Xgeva, check out this article. But certain choices and habits accelerate the process. kidney disease (or if you are on dialysis); a weak immune system (caused by disease or by using certain medicines); hypoparathyroidism (decreased functioning of the parathyroid glands); any condition that makes it hard for your body to absorb nutrients from food (malabsorption); if you are scheduled for a dental procedure; if you cannot take daily calcium and vitamin D; or. But, in some cases, alcohol can affect your balance and increase your risk for falls. You should not take Prolia if youve ever had an allergic reaction to Prolia or any of its ingredients. In addition to treating osteoporosis, which is described just above, Prolia also has other uses. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.) But weight gain may be a symptom of a side effect called peripheral edema. (A low blood calcium level is a possible side effect of Prolia.). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you cant properly absorb calcium or other minerals, be sure to talk with your doctor before using Prolia. How long will I need to keep taking Prolia? If youd like a detailed comparison of Prolia versus Boniva, view this article. You may also want to do some research on your own. It may also be higher if you have dental work done while youre taking Prolia. Continue reading, Prolia is a prescription medicine injected under the skin (called a subcutaneous injection) and is given once every 6 months. Nausea can sometimes be a symptom of severe constipation. They might also recommend physical therapy, massage therapy, or using a heating pad. Prolia can cause many serious side effects. It could harm the unborn baby or cause birth defects. And you should continue using birth control for at least 5 months after stopping Prolia. A few examples of bisphosphonates include: If youd like to know more about using a bisphosphonate for your condition, talk with your doctor. But hair loss has been reported by people who have taken Prolia since then. And they want you to get the best care possible. What should I know about Prolia vs. Tymlos? Prolia is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well. If you have any questions about Prolias side effects, talk with your doctor. Learn strategies you can use today. (Hint: it's not just. These problems may include: Your risk for mouth-related side effects may be higher if you have problems with your teeth. With bone loss, your body loses old bone tissue faster than it makes new bone tissue. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.). Prolia is a prescriptionmedicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments for breast cancer that has not spread to other parts of the body. Prolia is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments This increases your risk for bone fractures. Common interactions include nausea among females and fatigue among males. They have some similar uses and side effects, but they also have some differences. Vertigo (dizziness) was reported in some people who received Prolia for osteoporosis, but this was a less common side effect. Is the ketogenic diet right for autoimmune conditions? With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Drug class: Miscellaneous bone resorption inhibitors. In addition, Prolia may also be used off-label for other conditions that cause bone loss or loss of bone mineral density. Prolia can cause peripheral edema (fluid retention) or swelling, and this may lead to weight gain in some people. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Our website services, content, and products are for informational purposes only. I am taking Prolia and just saw that it's important to take Calcium because Prolia takes the calcium out of the blood and that can cause problems. Its important to tell your doctor if you have serious or ongoing side effects. But if they become bothersome, talk with your doctor or pharmacist. Symptoms of a fracture include new or unusual pain in your hip, groin, or thigh. Your doctor can also advise you on symptoms of low calcium to look for. If you want to stop taking Prolia, tell your doctor. If youd like to learn more about Prolia, talk with your doctor or pharmacist. Coral calcium is also used in maxillofacial surgery and bone grafting. American Dental Association (ADA) recommendations say that tooth extractions are allowable if needed during Prolia treatment, if both you and your dentist agree. Prolia also has other uses, which are described in the next section below. Do not treat yourself. If you have questions about treatment options for osteopenia or arthritis, talk with your doctor. To learn more about these two drugs, check out this drug article. Side effects that you should report to your doctor or health care professional as soon as possible: Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): This list may not describe all possible side effects. As with most drugs, Prolia can cause an allergic reaction in some people. Mild side effects of Prolia that have been reported include: Mild side effects of many drugs may go away within a few days or a few weeks. Keep out of the reach of children and pets. They can help answer any questions you have about side effects from taking the drug. (Biosimilars are like generic drugs. (Biosimilars are like generic drugs. These side effects include: Your risk for these serious side effects may be higher if youre older and have certain dental procedures. For women with osteoporosis after menopause at high risk for fracture. Your low blood calcium must be treated before you receive Prolia. How long will the side effects of Prolia last? Last medically reviewed on November 29, 2022. They may be able to help you identify the cause. For this reason, some calcium supplements are combined with vitamin D. This vitamin is available in two forms, vitamin D 2 (ergocalciferol) and vitamin Generic name: denosumab (Prolia) [den-OH-sue-mab] Your doctor or health care professional may order blood tests and other tests to see how you are doing. Take calcium and vitamin D as your doctor tells you to help prevent low blood calcium. Talk with your doctor or health care professional about your birth control options while taking this medicine. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Some research has shown that alcohol consumption may increase your risk of osteoporosis, a bone fracture or impaired healing after a fracture. Compared to other osteoporosis treatments, only Proliais1 shot every 6 months. Symptoms of a severe allergic reaction can include swelling under your skin, typically in your eyelids, lips, hands, or feet. Protect from light and do not freeze. After you have taken Prolia out of the refrigerator, you may keep it at room temperature for up to 14 days. Tell your doctor if you become pregnant. Continue reading, Prolia (denosumab) does increase bone density. You will receive your Prolia injection from your healthcare provider at a their office or clinic. When estrogen levels drop, your risk of osteoporosis goes up. For more information about how these medications compare with each other, ask your doctor. DENOSUMAB (den oh sue mab) slows bone breakdown. But if you think youre having a medical emergency, call 911 or your local emergency number. You can use the study as a second opinion to make health care decisions. Prolias manufacturer also provides some self-injection instructions, as well as a video to show you how to inject Prolia. Be sure to talk with your doctor about which medication is right for you. Theyre commonly used to treat osteoporosis. Youll receive Prolia from a healthcare professional as an injection under the skin in one of the following areas: Prolia contains the active drug denosumab, which is a biologic medication. WebTake calcium and vitamin D as directed by your doctor, usually 1000 milligrams of calcium and at least 400 IU of vitamin D daily. Sciatica was a less common side effect in females* who received Prolia for osteoporosis after menopause. Prolia comes with a warning about a low level of calcium in the blood. Both are prescription medicines. The lists below describe some of the more common side effects that Prolia may cause. With arthritis, you have pain and inflammation of your joints. Its used to lower the risk of bone fractures in people with certain other conditions. Hair loss with Prolia was reported after the drugs initial studies were done and it was approved for use. Your doctor will explain how Prolia will be given to you. Prolia is also used to treat glucocorticoid-induced osteoporosis in men and women at high risk of bone fracture. eHealthMe is studying from 138,307 Prolia users for its effectiveness, alternative drugs and more. The drug may increase the risk of pregnancy loss. Hair loss with Prolia is rare, and whether Prolia is responsible for this effect isnt known. But they each work differently because Prolia is a monoclonal antibody (it may also be called a miscellaneous bone resorption agent) and Reclast is a bisphosphonate which means they have different side effects, other uses, tolerability, and effectiveness profiles. Common side effects of this osteoporosis treatment injection include muscle, joint, and back pain. Yes, if recommended by your doctor, you can stop taking Prolia. Take only the amount of calcium and vitamin D that your doctor has prescribed. For Prolia, talk to your pediatrician regarding the use of this medicine in children. What Health Changes Should You Expect Postmenopause? What osteoporosis medications are there, and what side effects do they have? How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://www.ada.org/en/member-center/oral-health-topics/osteoporosis-medications, https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/125320s210lbl.pdf, New clues to slow aging? But before taking Prolia, be sure to tell your doctor about all medications you take (including prescription and over-the-counter types). Research has shown people who take Prolia are at an increased risk of serious infections leading to hospitalizations, including endocarditis and serious infections of the skin, abdominal, urinary tract, and ear. Usually, but it depends. If youve had surgery on your thyroid or parathyroid glands, you may have an increased risk of a low level of calcium in your blood. Talk with them about your health and any concerns you have about Prolia and its effects. Do not take this medicine with any of the following medications: This medicine may also interact with the following medications: This list may not describe all possible interactions. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. All rights reserved. Youll receive Prolia doses from a healthcare professional. Denosumab is contraindicated in women with hypocalcaemia. Having a tooth extraction while youre using Prolia may increase your risk for these side effects. In fact, bone breakdown is higher in the first several months after you stop Prolia. Weakness and tingling can also occur. Musculoskeletal pain from Prolia is mild or manageable for most people. Its important to practice good oral hygiene during Prolia treatment. These are not all the possible side effects of Prolia. WebNow that Im taking Prolia, do I still need calcium and vitamin D? Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The drug may also be used off-label for osteopenia, but usually, you dont need medications for osteopenia. They may give you tips on managing a body weight thats healthy for you. Talk with your doctor about the best options for treating your condition. Web You will receive Prolia 1 time every 6 months. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. A biologic drug is made from parts of living organisms. Biosimilars usually cost less than brand-name drugs. Studies have found that Prolia is generally safe and effective to treat osteoporosis and certain types of bone loss. Fracture in the spine after stopping Prolia treatment. Peripheral edema is a less common side effect that was reported in clinical studies of females* who received Prolia for osteoporosis after menopause. You should receive your missed injection as soon as possible. Lifestyle changes that can help improve cholesterol levels include exercising regularly and eating a healthy diet. According to the American Dental Association, your risk of this problem may increase if you receive denosumab (the active drug in Prolia) for longer than 2 years. If your doctor says this is safe for you, youll be shown how to inject the medication. It is often used in osteoporosis. Hair loss wasnt reported as a side effect during clinical trials of Prolia. The two most common forms of arthritis are osteoarthritis and rheumatoid arthritis (RA). It is important not to miss your dose. A solid routine can help to strengthen your muscles and bones, which helps to lower your, If you have osteoporosis, diet plays a vital role in managing your condition. Prolia solution is available in one strength: 60 milligrams per milliliter (mg/mL). Theyll do this with certain tests, such as a bone scan or ultrasound. You should also talk with your doctor if you have nausea during treatment. Talk with your doctor about which medication is right for you. Our phase IV clinical studies alone cannot establish cause-effect relationship. The conditions and factors to consider include: Upcoming dental procedures. This is because the drug may be harmful to a growing fetus. WebProlia is used to treat osteoporosis in women after menopause and in men, and in people Be sure to talk with your doctor about your health history before you take Prolia. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Here are a few questions to consider asking your doctor: You can also learn more about osteoporosis treatment options here. Allergic reaction. Stopping Prolia doesnt cause withdrawal symptoms. Bone pain from Prolia may be most noticeable in your arms and legs. such as inflammation of your skin (dermatitis), rash, and eczema have been reported. This is because its not known if Prolia is safe to receive while breastfeeding. You do not give Prolia to yourself. These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Prolia isnt known to cause any harmful interactions with alcohol. If your Prolia treatment is stopped, talk to your doctor about other medicine that Do not reuse a needle or syringe. Prolia is usually given once every 6 months. There is a potential for serious side effects to an unborn child. WebDrug interactions are reported among people who take Prolia and Calcium. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing. Call your doctor for medical advice about side effects. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia. So your healthcare provider will likely ask you to take calcium and vitamin D supplements if youre not taking them already. Osteoporosis medications and medication-related osteonecrosis of the jaw. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. This is because your body doesnt make enough bone, or it loses bone faster than it makes new bone. Constipation was also reported as a side effect in females using Prolia for osteoporosis. With peripheral edema, fluid builds up in your body and causes swelling in your arms and lower legs. These lists dont include all possible side effects. For example, in the studies, people taking Prolia for up to 8 years didnt have significant side effects compared with people taking a placebo. It is not known if the use of Prolia over a long period of time may cause slow healing of broken bones. Common If you have more questions about what to expect with dental procedures while youre taking Prolia, talk with your doctor or dentist. Prolia can also cause low calcium levels. In addition, your doctor will most likely recommend that you take calcium and vitamin D supplements while taking bisphosphonates, since vitamin D helps your body to absorb calcium. Although its rare, your doctor may give you the option to self-inject Prolia at home. They may recommend ways to ease your symptoms and determine whether you should keep taking Prolia. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. No, Prolia isnt a bisphosphonate. These side effects may be temporary, lasting a few days or weeks. Its recommended that calcium and vitamin D supplements be taken with Prolia. Some people may have dental or jaw-related issues with Prolia use. It is given by a health care professional in a hospital or clinic setting. Other side effects may continue for as long as you receive the medication, but they can often be relieved with other treatments. Dizziness from Prolia is usually mild and may go away on its own within a few days or weeks. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. Dietary calcium is considered safe, but too much calcium in the form of supplements might have some health risks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Prolia is a prescription medicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments The most common medications prescribed to lower cholesterol are statins. You can learn more about how we ensure our content is accurate and current by reading our. Youll likely receive Prolia long term if you and your doctor decide that the drug is effective and safe for you.
How To Prevent Medical Kidnapping,
Fresh Sugar Cane Sticks For Sale,
Car Accident In Sumter County, Fl Today,
Articles S